Chelation Therapy and Toxic Metals

In Italy chelation therapy is performed intravenously using the chemical agent EDTA (Ethylene Diamine Tetra-Acetic Acid), which is a molecule capable of binding to metal ions, forming inactive soluble compounds. This allows them to be eliminated from the body by the kidneys and the urine.

There are other substances used in other countries for this purpose: DMPS (also applied transdermally) and DMSA (also used for oral administration).

Each toxic metal has an affinity for a particular organ, called target organ, and migrates to the tissues of that organ. The mechanism through which toxic metals act is to block the activity of numerous enzymatic compounds causing metabolic and energetic damage to the cells of the body. The level of heavy metals found in the blood or in the urine is not a reliable indication of the level of intoxication, because the metals deposit and accumulate in the tissues, leaving only small amounts in the blood.

Neither do hair tissue mineral analysis (HTMA) nor saliva testing provide reliable results, because the metabolic systems may be inefficient in the elimination of toxins (for example due to L-glutathione deficiency) which can cause the incapacity to expel metals through the hair roots or the saliva.

EDTA binds to metal ions which are freely circulating in the system: following the reduction of their concentration in the blood, a re-equilibrium is reached with the diffusion of those deposited in the tissues, and so on until most of them are removed.

It is a slow process requiring time:

usually one phleboclysis (IV drip) is administered per week, followed by a maintenance period where treatments are given less frequently. EDTA binds to metals in a selective way, according to the affinity is has with those metals, starting with calcium, then iron, aluminium, cadmium, lead and mercury. This binding selectivity is also dependent on the concentration of each metal. The therapy must be carried out under the supervision of an expert medical practitioner, who will decide on the controls necessary for each individual case.

EDTA phleboclysis is also used as a diagnostic tool (Provocation or Challenge test):

after the infusion, urine is collected for a precise time period and tested for the presence of heavy metals. Chelation therapy is also used in the treatment of cardiocirculatory problems. Calcium and iron deposits in the plaque (which builds up on the tissue lining the arteries), if not yet hardened, have been seen to be removable by EDTA. Once the lumen and the elasticity of the blood vessels, especially the capillaries, have been restored, a notable improvement in correlated symptoms is achieved.

For further information, consult the articles by Dr. Fiamma Ferraro in the magazine “Scienza e Conoscenza” numbers 40 and 41, 2012.

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